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Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation that produces them more likely to benefit from naltrexone, weighed against about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are available online ( inside the journal Neuropsychopharmacology and are published in a upcoming print edition of the journal. Using two separate drugs to shed pounds can be very effective you will find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the individuals who go through it you should err along the side of caution and permit the FDA do its job and demand some research be done so your public recognizes the side effects and perils associated with the medications before we bring them. Keep in mind that drug companies will be in business to earn money and that they would say almost anything to keep people on the medications. Researchers found out that participants using this drug for any year, lost excess weight within one month and have kept the weight off through the 56 weeks in the study. Contrave is really a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of multiple active ingredient, which may make them more potent and safer. Combo-pilling could be the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling to lose weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular will be the fact that since right now there aren't long term prescription diet pills that have been licensed by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications although some people might of the combinations happen to be rejected or have yet to be licensed by the FDA. Seizures are a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise blood pressure and heartbeat, and mustn't be used in people who have a history of heart attack or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure levels, and also by you aren't heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients having a history of heart attack or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients to the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. The most common side effects with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.