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Using two separate drugs to lose weight naturally can be very effective you'll find combinations as you're watching FDA now awaiting approval. When dealing with fat loss and the those who go through it one should err to the side of caution and allow FDA do its job and demand some research be done so the public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies will be in business to generate income and that they would say everything to keep people on their own medications. Researchers found out that participants taking this drug for the year, dropped excess weight within 4 weeks and have kept the extra weight off throughout the 56 weeks of the study. Contrave is often a combination with the drugs naltrexone and bupropion, which usually reflect a fresh trend of weight-loss drugs which are made up of more than one active ingredient, which may make them more potent and safer. Combo-pilling could be the newest fad or in addition to this the newest into the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight reduction has been around since the eighties. The biggest reason that employing a combination of pills is now popular is the fact that as of right now there are not any long term prescription weight loss supplements that have been licensed by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications even though some of the combinations are already rejected or have yet to be licensed by the FDA. Seizures really are a side effect with Contrave and mustn't be taken in people who have seizure disorders. The drug also can raise blood pressure levels and heart rate, and really should not be used in those with a history of cardiac event or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug. The FDA also warned that Contrave can raise hypertension and heartbeat and must not used in patients with uncontrolled high blood pressure levels, in addition to by anyone with heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients using a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for smoking cessation. 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